PyMOL installation with the "conda" Package Manager

PyMOL 2.5 and later

(Updated June 05, 2025)

Since PyMOL 2.5, our pymol conda packages are based on conda-forge. The following command will install PyMOL on Windows, macOS or Linux into a conda environment:

conda install -c conda-forge -c schrodinger pymol-bundle

macOS Specifics

macOS-ARM (M1+)

We currently do not support Native Mac ARM on conda-forge. Thus, you will need to first create an X86-64 environment:

conda create --platform osx-64 --name <CUSTOM_ENV_NAME>

Then activate the environment:

conda activate <CUSTOM_ENV_NAME>

then follow the instructions below.

All macOS platforms:

On macOS, you need this command in addition:

pip install PyQt5

Previous versions

For PyMOL 2.0 to 2.4, this command should be sufficient:

conda install -c schrodinger pymol

After the installation is complete:

pymol

to launch PyMOL.